Often, Variants of Uncertain Significance (VUS) are identified in patients who undergo genetic testing. VUS is simply a classification given to a genetic variant when there is either conflicting or too little evidence to classify the variants as harmful or benign. VUSs have only a small chance of actually causing disease and most VUSs are eventually discovered to be benign. However, the true clinical meaning of any VUS is still uncertain. VUSolve® is a pioneering service provided by the Center for Genomic Interpretation that allows, in some circumstances, for the discovery of the true clinical meaning of a patient’s VUS.
Through the VUSolve® service, CGI scientists will first evaluate your VUS to determine whether the clinical meaning of the VUS is likely to be discovered through forensic genealogy. If CGI scientists determine a case as being a strong candidate for VUSolve®, CGI scientists will then work with you to determine whether or not you wish to engage in a forensic genealogy project to potentially uncover the true meaning of the VUS.
Click to button below to contact CGI for more information about the VUSolve paid service for your specific VUS.